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Filtered Search Results
Medchemexpress LLC Diethyl maleate | 141-05-9 | MFCD00009191 | 98.7% | 172.18 | C8H12O4 | 100mg
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Diethyl maleate (DEM) is an orally available effective glutathione (GSH) depletor that crosses the blood-brain barrier Diethyl maleate covalently binds irreversibly to GSH via glutathione S-transferase with an in vitro IC50 of 0 1-0 5 mM Diethyl maleate selectively depletes GSH in liver lung and brain tissues exacerbating oxidative stress and enhancing hyperbaric oxygen toxicity Diethyl maleate promotes precursor amino acid uptake and in turn promotes GSH synthesis by upregulating the activity of the cystine-glutamate transporter XO- Diethyl maleate can be used to study redox homeostasis and GSH protection mechanisms in oxidative stress-related diseases such as hyperbaric oxygen injury and metabolic diseases[1][2][3]
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eMolecules Ambeed Benzyl propiolate 100mg 784395629 A332728 0 000 14447-01-9 MFCD11976128 160 172 C10H8O2
Ambeed Benzyl propiolate 100mg 784395629 A332728 0 000 14447-01-9 MFCD11976128 160 172 C10H8O2
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Selleck Chemical LLC Indacaterol Maleate S3083-5mg
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Indacaterol (QAB149) is an ultra-long-acting -adrenoceptor agonist with pKi of 7 36 for 1-adrenoceptor and pKi of 5 48 for 2-adrenoceptor
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eMolecules 5089-70-3 | (3-Chloropropyl)triethoxysilane | Ambeed | MFCD00018985 | 240.800 | C9H21ClO3Si | 97.000 | CCO[Si](CCCCl)(OCC)OCC | 25g | 491684614
(3-Chloropropyl)triethoxysilane | Ambeed | 5089-70-3 | MFCD00018985 | 240.800 | C9H21ClO3Si | 97.000 | CCO[Si](CCCCl)(OCC)OCC | 25g | 491684614
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eMolecules 922-67-8 | Methyl propiolate | Ambeed | MFCD00008572 | 84.074 | C4H4O2 | 98.000 | COC(=O)C#C | 25g | 552720844
Methyl propiolate | Ambeed | 922-67-8 | MFCD00008572 | 84.074 | C4H4O2 | 98.000 | COC(=O)C#C | 25g | 552720844
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Medchemexpress LLC IMMH-010 maleate | 2541982-47-0 | 99.8% | 756.04 | 1 MG
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IMMH-010 maleate is a prodrug that serves as a novel PD-L1 inhibitor, exhibiting potential antitumor activity for the treatment of neurological disorders and advanced malignant solid tumors. It is rapidly converted to its active form, YPD-29B, following oral administration. IMMH-010 maleate is poised for advancing research in the field of PD-L1 inhibitors and related therapeutic applications.
- Novel PD-L1 inhibitor
- Exhibits potential antitumor activity for neurological disorders and advanced malignant solid tumors
- Prodrug that rapidly converts to its active form, YPD-29B, following oral administration
- Poised for advancing research in the field of PD-L1 inhibitors and related therapeutic applications
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eMolecules 103-41-3 | Benzyl cinnamate | Oakwood Chemical | MFCD00004789 | 238.286 | C16H14O2 | 99.000 | O=C(OCc1ccccc1)\C=C\c1ccccc1 | 25g | 537707346
Benzyl cinnamate | Oakwood Chemical | 103-41-3 | MFCD00004789 | 238.286 | C16H14O2 | 99.000 | O=C(OCc1ccccc1)\C=C\c1ccccc1 | 25g | 537707346
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TARGETMOL CHEMICALS INC ASENAPINE MALEATE 100MG
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Also available in 5 mg 10 mg 25 mg 50 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Asenapine Maleate (Org 5222 maleate) is a second generation (atypical) antipsychotic agent that is taken sublingually and used in the treatment of schizophrenia and manic or mixed episodes associated with bipolar 1 disorder. Asenapine is associated with a low rate of transient and mild serum aminotransferase elevations during therapy but has not been linked to instances of clinically apparent acute liver injury. purity: 99%
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Apexbio Technology LLC L-693,403 maleate 207455-21-8 10mg
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L-693 403 maleate (CAS 207455-21-8) is a small molecule exhibiting high affinity and selectivity for sigma ( ) receptors By modulating receptor-mediated signaling pathways it influences neuronal signal transduction at the molecular level Preclinical studies indicate that L-693 403 maleate possesses analgesic properties likely through its regulatory effects on neural activity Owing to these pharmacological characteristics it is utilized in exploratory research on neurological disorders supporting its value as a tool compound in the investigation of neural modulation mechanisms
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eMolecules 35952-69-3 | Ambeed | (2-Bromopropoxy)trimethylsilane | 1g | 572861989 | A1039449 | MFCD24477135 | 211.174 | C6H15BrOSi
Ambeed | 1-(2-(4-((4-Carbamoylpiperidin-1-yl)methyl)-N-methylbenzamido)ethyl)piperidin-4-yl [11-biphenyl]-2-ylcarbamate | 5mg | 514324562 | A642503 | 864750-70-9 | MFCD28386316 | 597.760 | C35H43N5O4
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Medchemexpress LLC Ilginatinib maleate (NS-018 maleate) | 1354799-87-3 | 99.87% | 505.50 | 1 ML
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Ilginatinib maleate (NS-018 maleate) | 1354799-87-3 | 99.87% | 505.50 | 1 ML
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Medchemexpress LLC Trimebutine (maleate) | 34140-59-5 | 99.7% | 1 ML
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Trimebutine (maleate) | 34140-59-5 | 99.7% | 1 ML
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1PLUSCHEM LLC Ingenol mebutate | 75567-37-2 | 430.5 g/mol | 1MG
Ingenol mebutate | 75567-37-2 | 430.5 g/mol | 1MG
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Medchemexpress LLC U-99194 maleate (U-99194A) | 234757-41-6 | 99.2% | 50 MG
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U-99194 (PNU-99194) maleate is a selective and potent dopamine D3 receptor antagonist. It inhibits the activation of D3 receptors mediated by endogenously released dopamine or exogenous D3 agonists. This compound can be used for the study of dopamine D3 receptor-mediated motor disorders, particularly kinetic tremors.
- Selective, potent dopamine D3 receptor antagonist (Ki = 160 nM).
- Inhibits D3 receptor activation.
- Abrogates IPSC-suppressive effect of D3 agonist PD 128907 in rat hippocampal slices.
- Significantly suppresses nicotine-induced tremor in mice.
- Useful for studying dopamine D3 receptor-mediated motor disorders, especially kinetic tremors.
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Medchemexpress LLC Filgotinib (maleate) | 1802998-75-9 | 99.9% | 541.58 | 5 MG
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Filgotinib maleate is a selective, orally available JAK1 inhibitor with anti-inflammatory and antiviral activities. It effectively inhibits JAK1, JAK2, JAK3, and TYK2. It also inhibits HIV-1 driven gene transcription and reduces proliferation of HIV-1 infected cells. It can be used in the study of rheumatoid arthritis and inflammatory bowel disease.
- Inhibits differentiation of Th2 cells and Th1 cells.
- Produces dose-dependent bone damage protection.
- Prevents the development of inflammation in animal models of collagen-induced arthritis.
- Reduces inflammatory cell infiltration.
- Protects articular cartilage and bone.
- Reduces serum levels of inflammatory cytokines and chemokines.
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